.break-report[data-astro-cid-wphdnyj3]{--ink:#202c42;--muted:#536178;--blue:#2855cf;--line:#dce2ed;color:var(--ink);--lightningcss-light:initial;--lightningcss-dark: ;color-scheme:light;background:#fff;min-width:0;padding:1px 0 4rem}.breadcrumbs[data-astro-cid-wphdnyj3]{max-width:72rem;margin:auto;padding:8px 0}.breadcrumbs[data-astro-cid-wphdnyj3] .page-breadcrumb{width:calc(100% - 3rem)}.breadcrumbs[data-astro-cid-wphdnyj3] .page-breadcrumb ol,.breadcrumbs[data-astro-cid-wphdnyj3] .page-breadcrumb [aria-current=page]{color:var(--muted)}.story[data-astro-cid-wphdnyj3]{min-width:0;max-width:50rem;margin:1.4rem auto 0;padding:0 1.5rem}.story[data-astro-cid-wphdnyj3] a[data-astro-cid-wphdnyj3]{color:var(--blue);text-underline-offset:.18em;text-decoration:underline}.story[data-astro-cid-wphdnyj3] [data-astro-cid-wphdnyj3]:is(a,button,input,summary,[tabindex]):focus-visible{outline-offset:4px;outline:3px solid #b8412d}.eyebrow[data-astro-cid-wphdnyj3]{letter-spacing:.04em;color:var(--blue);flex-wrap:wrap;align-items:center;gap:.55rem;margin:0 0 .9rem;font-size:.78rem;font-weight:700;display:flex}.eyebrow[data-astro-cid-wphdnyj3] a[data-astro-cid-wphdnyj3]{background:#edf3ff;border-radius:4px;padding:.25rem .6rem;text-decoration:none}.story-heading[data-astro-cid-wphdnyj3] h1[data-astro-cid-wphdnyj3]{letter-spacing:-.045em;color:#17294b;margin:0 0 1.1rem;font-size:clamp(2.5rem,5.5vw,3.8rem);font-weight:760;line-height:1.08}.dek[data-astro-cid-wphdnyj3]{color:var(--muted);margin:0 0 1.3rem;font-size:1.2rem;line-height:1.65}.byline[data-astro-cid-wphdnyj3]{color:var(--muted);flex-wrap:wrap;align-items:center;gap:.3rem .45rem;margin:0 0 1.6rem;font-size:.82rem;display:flex}.byline[data-astro-cid-wphdnyj3] a[data-astro-cid-wphdnyj3]{font-weight:600}.prose[data-astro-cid-wphdnyj3]{overflow-wrap:break-word;font-size:1.075rem;line-height:1.85}.prose[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{margin:1.15rem 0}.prose[data-astro-cid-wphdnyj3] h2[data-astro-cid-wphdnyj3]{letter-spacing:-.025em;color:#17294b;margin:1rem 0;font-size:1.75rem;font-weight:730;line-height:1.25}.prose[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{font-size:1.15rem;font-weight:700;line-height:1.4}.prose[data-astro-cid-wphdnyj3] li[data-astro-cid-wphdnyj3]{margin:.65rem 0}.prose[data-astro-cid-wphdnyj3] section[data-astro-cid-wphdnyj3]{margin-top:3.2rem;scroll-margin-top:1.5rem}.prose[data-astro-cid-wphdnyj3] .chapter-label[data-astro-cid-wphdnyj3]{letter-spacing:.07em;color:var(--accent);margin:0 0 .8rem;font-size:.72rem;font-weight:750}.chapter-nav[data-astro-cid-wphdnyj3]{border:1px solid var(--line);border-radius:7px;grid-template-columns:repeat(4,minmax(0,1fr));margin:2.1rem 0 2.7rem;display:grid;overflow:hidden}.chapter-nav[data-astro-cid-wphdnyj3] a[data-astro-cid-wphdnyj3]{border-top:4px solid var(--accent);background:var(--pale);color:var(--ink);padding:.9rem .8rem;text-decoration:none}.chapter-nav[data-astro-cid-wphdnyj3] a[data-astro-cid-wphdnyj3]+a[data-astro-cid-wphdnyj3]{border-left:1px solid var(--line)}.chapter-nav[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{color:var(--accent);letter-spacing:.04em;margin-bottom:.3rem;font-size:.6rem;font-weight:750;line-height:1.7;display:block}.chapter-nav[data-astro-cid-wphdnyj3] strong[data-astro-cid-wphdnyj3]{font-size:.84rem;line-height:1.3;display:block}.visual[data-astro-cid-wphdnyj3]{border:1px solid color-mix(in srgb,var(--accent) 22%,white);border-top:5px solid var(--accent);background:var(--pale);border-radius:8px;margin:1.6rem 0 1.8rem;padding:1.5rem 1.5rem 0;overflow:hidden}.visual-heading[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{letter-spacing:.075em;color:var(--accent);font-size:.64rem;font-weight:750}.visual-heading[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{letter-spacing:-.02em;margin:.35rem 0 .4rem;font-size:1.4rem;line-height:1.25}.visual-heading[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{color:var(--muted);margin:.4rem 0 1.4rem;font-size:.78rem;line-height:1.6}.visual[data-astro-cid-wphdnyj3] figcaption[data-astro-cid-wphdnyj3]{color:var(--muted);border-top:1px solid color-mix(in srgb,var(--accent) 20%,white);background:#fff;margin:1.4rem -1.5rem 0;padding:1rem 1.5rem;font-size:.77rem;line-height:1.7}.data-table[data-astro-cid-wphdnyj3]{border:1px solid var(--line);background:#fff;border-radius:6px;margin:1.5rem 0}.data-table[data-astro-cid-wphdnyj3] summary[data-astro-cid-wphdnyj3]{cursor:pointer;color:#2855cf;min-height:48px;padding:.85rem 1rem;font-size:.85rem;font-weight:650}.table-scroll[data-astro-cid-wphdnyj3]{padding:0 1rem 1rem;overflow-x:auto}.table-scroll[data-astro-cid-wphdnyj3] table[data-astro-cid-wphdnyj3]{border-collapse:collapse;text-align:left;width:100%;min-width:310px;font-size:.78rem}.table-scroll[data-astro-cid-wphdnyj3] caption[data-astro-cid-wphdnyj3]{text-align:left;color:var(--muted);padding:.5rem 0;font-size:.75rem}.table-scroll[data-astro-cid-wphdnyj3] th[data-astro-cid-wphdnyj3],.table-scroll[data-astro-cid-wphdnyj3] td[data-astro-cid-wphdnyj3]{border-bottom:1px solid var(--line);padding:.5rem .6rem}.table-scroll[data-astro-cid-wphdnyj3] th[data-astro-cid-wphdnyj3]{font-weight:650}.sources[data-astro-cid-wphdnyj3]{border-top:1px solid #dce2ed;padding-top:1rem}.sources[data-astro-cid-wphdnyj3]>p[data-astro-cid-wphdnyj3],.sources[data-astro-cid-wphdnyj3] li[data-astro-cid-wphdnyj3]{font-size:.86rem;line-height:1.8}.sources[data-astro-cid-wphdnyj3] ol[data-astro-cid-wphdnyj3]{padding-left:1.3rem}.sources[data-astro-cid-wphdnyj3] .source-date[data-astro-cid-wphdnyj3]{color:#536178;font-size:.75rem}.downloads[data-astro-cid-wphdnyj3]{color:#fff;background:#17294b;border-radius:8px;margin:25px 0;padding:25px}.downloads[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{color:#ffdb7a;letter-spacing:.07em;font-size:.64rem;font-weight:750}.downloads[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{color:#fff;margin:.5rem 0;font-size:1.4rem;line-height:1.3}.downloads[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{color:#d1def0;margin:.7rem 0 1.2rem;font-size:.85rem;line-height:1.7}.download-links[data-astro-cid-wphdnyj3]{grid-template-columns:1fr 1fr;gap:9px;display:grid}.download-links[data-astro-cid-wphdnyj3] a[data-astro-cid-wphdnyj3]{color:#fff;background:#223b61;border:1px solid #6e83a3;border-radius:5px;justify-content:space-between;align-items:center;gap:8px;min-height:47px;padding:12px 13px;font-size:.73rem;line-height:1.5;text-decoration:none;display:flex}.download-links[data-astro-cid-wphdnyj3] a[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{color:#d1def0;white-space:nowrap;font-size:.62rem}.download-links[data-astro-cid-wphdnyj3] a[data-astro-cid-wphdnyj3]:hover{background:#304f7b}.author[data-astro-cid-wphdnyj3]{border-top:1px solid var(--line);margin-top:2.4rem;padding-top:1.5rem;font-size:.85rem}.author[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{color:#536178;margin:.4rem 0;font-size:.8rem;line-height:1.7}.story-heading[data-astro-cid-wphdnyj3] h1[data-astro-cid-wphdnyj3]{font-size:clamp(2.4rem,5.2vw,3.65rem)}.story-heading[data-astro-cid-wphdnyj3] h1[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{color:#b8412d}.story-heading[data-astro-cid-wphdnyj3] .title-tail[data-astro-cid-wphdnyj3]{white-space:nowrap}.hero[data-astro-cid-wphdnyj3]{margin:1.7rem 0 2rem}.hero-panel[data-astro-cid-wphdnyj3]{color:#fff;background:#17294b;border-radius:10px;overflow:hidden}.hero-top[data-astro-cid-wphdnyj3]{letter-spacing:.06em;border-bottom:1px solid #354968;justify-content:space-between;align-items:center;gap:12px;padding:18px 25px;font-size:.61rem;font-weight:750;display:flex}.hero-tag[data-astro-cid-wphdnyj3]{color:#d1def0;letter-spacing:0;white-space:nowrap;background:#354968;border-radius:4px;padding:5px 8px;font-weight:500}.hero-heading[data-astro-cid-wphdnyj3]{padding:28px 30px 18px}.hero-heading[data-astro-cid-wphdnyj3] h2[data-astro-cid-wphdnyj3]{letter-spacing:-.035em;margin:0 0 14px;font-size:2.3rem;font-weight:750;line-height:1.12}.hero-heading[data-astro-cid-wphdnyj3] em[data-astro-cid-wphdnyj3]{color:#ffd574;font-style:normal}.hero-heading[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{color:#d1def0;margin:0;font-size:.88rem;line-height:1.7}.pause-strip[data-astro-cid-wphdnyj3]{justify-content:center;align-items:center;gap:25px;margin:12px 30px 25px;font-size:.78rem;display:flex}.pause-strip[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{color:#d1def0;border:1px solid #8097ba;border-radius:5px;padding:9px 18px}.pause-strip[data-astro-cid-wphdnyj3] i[data-astro-cid-wphdnyj3]{color:#afc6e9;font-style:normal}.pause-strip[data-astro-cid-wphdnyj3] strong[data-astro-cid-wphdnyj3]{color:#17294b;background:#ffd574;border-radius:5px;align-items:center;gap:10px;padding:9px 24px;font-size:.9rem;display:flex}.pause-strip[data-astro-cid-wphdnyj3] strong[data-astro-cid-wphdnyj3] b[data-astro-cid-wphdnyj3]{font-size:1.25rem;line-height:1}.hero-questions[data-astro-cid-wphdnyj3]{grid-template-columns:1fr 1fr;gap:16px;padding:0 30px;display:grid}.hero-questions[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]{color:#17294b;background:#dceaff;border-radius:7px;padding:20px;position:relative}.hero-questions[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]+div[data-astro-cid-wphdnyj3]{background:#ffe1d5}.question-icon[data-astro-cid-wphdnyj3]{float:right;color:#2855cf;font-size:2rem;line-height:1}.hero-questions[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]+div[data-astro-cid-wphdnyj3] .question-icon[data-astro-cid-wphdnyj3]{color:#a83a28}.hero-questions[data-astro-cid-wphdnyj3] small[data-astro-cid-wphdnyj3]{letter-spacing:.06em;font-size:.59rem;font-weight:750}.hero-questions[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{letter-spacing:-.02em;margin:12px 0 9px;font-size:1.3rem;font-weight:750;line-height:1.3}.hero-questions[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{margin:0;font-size:.8rem;line-height:1.7}.hero-foot[data-astro-cid-wphdnyj3]{color:#d1def0;text-align:center;margin:0;padding:22px 25px;font-size:.74rem;line-height:1.6}.hero[data-astro-cid-wphdnyj3] figcaption[data-astro-cid-wphdnyj3]{color:#536178;margin-top:.7rem;font-size:.75rem;line-height:1.65}.plot-key[data-astro-cid-wphdnyj3]{flex-wrap:wrap;gap:12px 23px;margin:0 0 15px;font-size:.7rem;display:flex}.plot-key[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{align-items:center;gap:8px;display:flex}.key-point[data-astro-cid-wphdnyj3]{background:#536178;border-radius:50%;width:11px;height:11px}.key-interval[data-astro-cid-wphdnyj3]{border-left:2px solid #536178;border-right:2px solid #536178;width:30px;height:12px;position:relative}.key-interval[data-astro-cid-wphdnyj3]:after{content:"";border-top:2px solid #536178;position:absolute;top:5px;left:0;right:0}.forest-chart[data-astro-cid-wphdnyj3]{background:#fff;border-radius:6px;padding:0 16px}.forest-row[data-astro-cid-wphdnyj3]{border-bottom:1px solid #dce2ed;padding:18px 0 14px}.forest-row[data-astro-cid-wphdnyj3]:last-child{border-bottom:0}.forest-heading[data-astro-cid-wphdnyj3]{justify-content:space-between;align-items:center;gap:12px;margin-bottom:12px;display:flex}.forest-heading[data-astro-cid-wphdnyj3] h4[data-astro-cid-wphdnyj3]{color:var(--series);margin:0;font-size:1rem;font-weight:750;line-height:1.3}.forest-heading[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{color:#536178;margin:4px 0 0;font-size:.7rem;line-height:1.5}.forest-heading[data-astro-cid-wphdnyj3]>strong[data-astro-cid-wphdnyj3]{color:var(--series);letter-spacing:-.025em;text-align:right;white-space:nowrap;font-size:1.65rem;line-height:1.2}.forest-heading[data-astro-cid-wphdnyj3] small[data-astro-cid-wphdnyj3]{letter-spacing:0;color:#536178;margin-top:3px;font-size:.69rem;font-weight:500;display:block}.forest-track[data-astro-cid-wphdnyj3]{height:34px;margin:0 10px;position:relative}.plot-grid[data-astro-cid-wphdnyj3]{border-left:1px solid #e0e6f0;position:absolute;top:0;bottom:0}.zero-line[data-astro-cid-wphdnyj3]{border-left:2px dashed #71819b}.interval[data-astro-cid-wphdnyj3]{background:var(--series);height:4px;position:absolute;top:16px}.interval[data-astro-cid-wphdnyj3]:before,.interval[data-astro-cid-wphdnyj3]:after{content:"";border-left:2px solid var(--series);height:14px;position:absolute;top:-5px}.interval[data-astro-cid-wphdnyj3]:before{left:0}.interval[data-astro-cid-wphdnyj3]:after{right:0}.estimate[data-astro-cid-wphdnyj3]{width:14px;height:14px;box-shadow:0 0 0 2px var(--series);background:var(--series);border:2px solid #fff;border-radius:50%;position:absolute;top:17px;transform:translate(-50%,-50%)}.row-reading[data-astro-cid-wphdnyj3]{color:#536178;flex-wrap:wrap;justify-content:space-between;gap:8px;margin-top:7px;font-size:.75rem;line-height:1.6;display:flex}.effect-axis[data-astro-cid-wphdnyj3]{color:#536178;height:33px;margin:0 26px;font-size:12px;position:relative}.effect-axis[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{position:absolute;top:8px;transform:translate(-50%)}.zero-note[data-astro-cid-wphdnyj3]{background:#dceaff;border-radius:5px;align-items:center;gap:14px;margin:10px 0 0;padding:13px 16px;display:flex}.zero-note[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{color:#2855cf;font-size:2rem;font-weight:750;line-height:1}.zero-note[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{margin:0;font-size:.75rem;line-height:1.6}.zero-note[data-astro-cid-wphdnyj3] strong[data-astro-cid-wphdnyj3]{display:block}.note[data-astro-cid-wphdnyj3]{background:#f4efff;border-left:4px solid #7040c7;margin:1.6rem 0;padding:1rem 1.2rem;font-size:.88rem;line-height:1.7}.note[data-astro-cid-wphdnyj3] strong[data-astro-cid-wphdnyj3]{color:#6032b3}.note[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{margin:.3rem 0 0}.protocol-timeline[data-astro-cid-wphdnyj3]{margin:24px 12px 0;padding-top:33px;position:relative}.protocol-blocks[data-astro-cid-wphdnyj3]{grid-template-columns:repeat(4,minmax(0,1fr));gap:4px;display:grid}.protocol-blocks[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]{text-align:center;background:#ffe1d5;border:1px solid #c6765f;border-radius:4px;padding:14px 8px}.protocol-blocks[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{letter-spacing:.04em;color:#933827;font-size:.65rem;font-weight:750;display:block}.protocol-blocks[data-astro-cid-wphdnyj3] b[data-astro-cid-wphdnyj3]{margin-top:7px;font-size:.8rem;font-weight:600;line-height:1.5;display:block}.switch-pins[data-astro-cid-wphdnyj3]{height:33px;position:absolute;top:0;left:0;right:0}.switch-pins[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{white-space:nowrap;color:#b8412d;font-size:.72rem;font-weight:700;position:absolute;transform:translate(-50%)}.switch-pins[data-astro-cid-wphdnyj3] i[data-astro-cid-wphdnyj3]{border-left:2px solid #b8412d;height:16px;position:absolute;top:22px;left:50%}.time-axis[data-astro-cid-wphdnyj3]{color:#536178;height:30px;font-size:12px;position:relative}.time-axis[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{position:absolute;top:6px;transform:translate(-50%)}.protocol-visual[data-astro-cid-wphdnyj3] .protocol-unit[data-astro-cid-wphdnyj3]{color:#536178;margin:0 0 0 12px;font-size:.72rem}.study-comparison[data-astro-cid-wphdnyj3]{grid-template-columns:1fr 1fr;gap:15px;margin:25px 0;display:grid}.study-comparison[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]{background:#edf3ff;border:1px solid #d2def4;border-top:4px solid #2855cf;border-radius:6px;padding:19px}.study-comparison[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]+div[data-astro-cid-wphdnyj3]{background:#f4efff;border-color:#7040c7 #ddd1f4 #ddd1f4}.study-comparison[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{color:#2855cf;letter-spacing:.04em;font-size:.63rem;font-weight:750}.study-comparison[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]+div[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{color:#7040c7}.study-comparison[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{margin:10px 0;font-size:1.1rem;line-height:1.3}.study-comparison[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{margin:0;font-size:.82rem;line-height:1.75}.newer-evidence[data-astro-cid-wphdnyj3]{background:#eef9f5;border-left:4px solid #08756b;margin:25px 0;padding:20px 23px}.newer-evidence[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{letter-spacing:.04em;color:#08756b;font-size:.63rem;font-weight:750}.newer-evidence[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{margin:8px 0;font-size:1.2rem}.newer-evidence[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{margin:.6rem 0 0;font-size:.86rem;line-height:1.75}.change-map[data-astro-cid-wphdnyj3]{grid-template-columns:repeat(3,minmax(0,1fr));gap:12px;margin:25px 0;display:grid}.change-map[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]{background:#edf3ff;border-top:4px solid #2855cf;border-radius:5px;padding:20px 16px}.change-map[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]:nth-child(2){background:#fff0f4;border-color:#b23b57}.change-map[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]:nth-child(3){background:#f4efff;border-color:#7040c7}.change-map[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{color:#2855cf;font-size:2rem;line-height:1}.change-map[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]:nth-child(2)>span[data-astro-cid-wphdnyj3]{color:#b23b57}.change-map[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]:nth-child(3)>span[data-astro-cid-wphdnyj3]{color:#7040c7}.change-map[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{margin:16px 0 8px;font-size:.93rem;line-height:1.3}.change-map[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{margin:0;font-size:.79rem;line-height:1.7}.three-separate[data-astro-cid-wphdnyj3]{color:#fff;background:#17294b;border-radius:6px;grid-template-columns:1fr auto 1fr auto 1fr;align-items:center;gap:13px;margin:25px 0;padding:22px;display:grid}.three-separate[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{font-size:.75rem;line-height:1.5}.three-separate[data-astro-cid-wphdnyj3] b[data-astro-cid-wphdnyj3]{color:#ffd574;letter-spacing:.05em;margin-bottom:7px;font-size:.59rem;display:block}.three-separate[data-astro-cid-wphdnyj3] i[data-astro-cid-wphdnyj3]{color:#d1def0;font-size:1.5rem;font-style:normal}fieldset[data-astro-cid-wphdnyj3]{border:0;min-width:0;margin:1.4rem 0;padding:0}legend[data-astro-cid-wphdnyj3],.return-label[data-astro-cid-wphdnyj3]{margin-bottom:.7rem;font-size:.86rem;font-weight:700;line-height:1.5;display:block}.activity-options[data-astro-cid-wphdnyj3]{grid-template-columns:repeat(3,minmax(0,1fr));gap:10px;display:grid}.activity-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3],.boundary-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]{font:inherit;cursor:pointer;color:#202c42;background:#fff;border:2px solid #8893a5;border-radius:6px;min-height:48px;position:relative}.activity-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]{text-align:left;min-width:0;padding:18px 12px}.activity-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{color:#2855cf;font-size:1.8rem;line-height:1;display:block}.activity-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]:nth-child(2)>span[data-astro-cid-wphdnyj3]{color:#b23b57}.activity-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]:nth-child(3)>span[data-astro-cid-wphdnyj3]{color:#7040c7}.activity-options[data-astro-cid-wphdnyj3] strong[data-astro-cid-wphdnyj3]{margin-top:12px;font-size:.8rem;font-weight:650;display:block}.selected-mark[data-astro-cid-wphdnyj3]{color:#0000;border:1px solid #8893a5;border-radius:50%;place-items:center;width:19px;height:19px;font-size:.72rem;font-style:normal;display:inline-grid}.activity-options[data-astro-cid-wphdnyj3] .selected-mark[data-astro-cid-wphdnyj3]{position:absolute;top:14px;right:11px}.planner[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3][aria-pressed=true]{border-color:#2855cf;box-shadow:0 0 0 1px #2855cf}.planner[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3][aria-pressed=true] .selected-mark[data-astro-cid-wphdnyj3]{color:#fff;background:#2855cf;border-color:#2855cf}.planner[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]:disabled,.planner[data-astro-cid-wphdnyj3] input[data-astro-cid-wphdnyj3]:disabled{opacity:.65;cursor:default}.boundary-options[data-astro-cid-wphdnyj3]{grid-template-columns:1fr 1fr;gap:10px;display:grid}.boundary-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]{justify-content:center;align-items:center;gap:9px;padding:12px 10px;font-size:.8rem;line-height:1.45;display:flex}.boundary-options[data-astro-cid-wphdnyj3] .selected-mark[data-astro-cid-wphdnyj3]{flex:none}.return-label[data-astro-cid-wphdnyj3]{margin-top:22px}.return-label[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{color:#536178;font-weight:400}.planner[data-astro-cid-wphdnyj3] input[data-astro-cid-wphdnyj3][type=text]{box-sizing:border-box;width:100%;min-height:48px;font:inherit;color:#202c42;background:#fff;border:2px solid #8893a5;border-radius:5px;padding:11px 12px;font-size:.86rem}.planner[data-astro-cid-wphdnyj3] input[data-astro-cid-wphdnyj3]::placeholder{color:#536178;opacity:1}.plan-note[data-astro-cid-wphdnyj3]{color:#fff;overflow-wrap:anywhere;background:#17294b;border-radius:6px;min-height:145px;margin-top:22px;padding:20px}.plan-note[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{letter-spacing:.06em;color:#ffd574;font-size:.61rem;font-weight:750}.plan-note[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{margin:9px 0 0;font-size:1.03rem;line-height:1.65}.plan-note[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]+p[data-astro-cid-wphdnyj3]{color:#d1def0;border-top:1px solid #526988;margin-top:12px;padding-top:12px;font-size:.84rem}.planner[data-astro-cid-wphdnyj3] .plan-explanation[data-astro-cid-wphdnyj3]{color:#536178;margin:13px 0;font-size:.76rem;line-height:1.7}.return-card[data-astro-cid-wphdnyj3]{background:#eef9f5;border:1px solid #c5e4da;border-top:4px solid #08756b;border-radius:6px;margin:25px 0;padding:22px}.return-card[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{letter-spacing:.05em;color:#08756b;font-size:.62rem;font-weight:750}.return-card[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{margin:7px 0 16px;font-size:1.3rem}.return-card[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]{grid-template-columns:1fr 1fr;gap:25px;display:grid}.return-card[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{margin:0;font-size:.82rem;line-height:1.7}.return-card[data-astro-cid-wphdnyj3] b[data-astro-cid-wphdnyj3]{margin-bottom:5px;display:block}@media (width<=640px){.breadcrumbs[data-astro-cid-wphdnyj3] .page-breadcrumb{width:calc(100% - 2rem)}.story[data-astro-cid-wphdnyj3]{margin-top:1rem;padding:0 1rem}.story-heading[data-astro-cid-wphdnyj3] h1[data-astro-cid-wphdnyj3]{font-size:2.55rem}.dek[data-astro-cid-wphdnyj3]{font-size:1.05rem}.byline[data-astro-cid-wphdnyj3]{font-size:.75rem}.hero-top[data-astro-cid-wphdnyj3]{padding:15px 18px;font-size:.56rem}.hero-tag[data-astro-cid-wphdnyj3]{padding:4px 6px;font-size:.53rem}.hero-heading[data-astro-cid-wphdnyj3]{padding:23px 20px 16px}.hero-heading[data-astro-cid-wphdnyj3] h2[data-astro-cid-wphdnyj3]{font-size:2rem}.hero-heading[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{font-size:.8rem}.pause-strip[data-astro-cid-wphdnyj3]{gap:12px;margin:10px 20px 20px;font-size:.7rem}.pause-strip[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{padding:8px 11px}.pause-strip[data-astro-cid-wphdnyj3] strong[data-astro-cid-wphdnyj3]{gap:7px;padding:8px 12px;font-size:.77rem}.hero-questions[data-astro-cid-wphdnyj3]{grid-template-columns:1fr;gap:12px;padding:0 20px}.hero-questions[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]{padding:19px}.hero-questions[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{margin:10px 0 7px;font-size:1.2rem}.hero-questions[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{font-size:.79rem}.hero-foot[data-astro-cid-wphdnyj3]{padding:20px;font-size:.72rem}.chapter-nav[data-astro-cid-wphdnyj3]{grid-template-columns:1fr 1fr}.chapter-nav[data-astro-cid-wphdnyj3] a[data-astro-cid-wphdnyj3]:nth-child(3){border-left:0}.prose[data-astro-cid-wphdnyj3]{font-size:1rem;line-height:1.8}.prose[data-astro-cid-wphdnyj3] h2[data-astro-cid-wphdnyj3]{font-size:1.5rem}.visual[data-astro-cid-wphdnyj3]{padding:1.1rem 1rem 0}.visual[data-astro-cid-wphdnyj3] figcaption[data-astro-cid-wphdnyj3]{margin:1.1rem -1rem 0;padding:.9rem 1rem;font-size:.73rem}.visual-heading[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{font-size:1.25rem}.plot-key[data-astro-cid-wphdnyj3]{gap:9px 15px;font-size:.75rem}.forest-chart[data-astro-cid-wphdnyj3]{padding:0 12px}.forest-heading[data-astro-cid-wphdnyj3] h4[data-astro-cid-wphdnyj3]{font-size:.95rem}.forest-heading[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{max-width:165px;font-size:.75rem}.forest-heading[data-astro-cid-wphdnyj3]>strong[data-astro-cid-wphdnyj3]{font-size:1.45rem}.forest-heading[data-astro-cid-wphdnyj3] small[data-astro-cid-wphdnyj3]{font-size:.69rem}.row-reading[data-astro-cid-wphdnyj3]{flex-direction:column;gap:2px;font-size:.75rem}.effect-axis[data-astro-cid-wphdnyj3]{margin:0 22px}.zero-note[data-astro-cid-wphdnyj3]{gap:11px;padding:12px}.zero-note[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{font-size:.7rem}.protocol-timeline[data-astro-cid-wphdnyj3]{margin-left:5px;margin-right:5px}.protocol-blocks[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]{padding:12px 3px}.protocol-blocks[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{font-size:.65rem}.protocol-blocks[data-astro-cid-wphdnyj3] b[data-astro-cid-wphdnyj3],.switch-pins[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{font-size:.72rem}.protocol-visual[data-astro-cid-wphdnyj3] .protocol-unit[data-astro-cid-wphdnyj3]{margin-left:5px;font-size:.72rem}.study-comparison[data-astro-cid-wphdnyj3]{grid-template-columns:1fr}.study-comparison[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{font-size:.83rem}.newer-evidence[data-astro-cid-wphdnyj3]{padding:18px}.change-map[data-astro-cid-wphdnyj3]{grid-template-columns:1fr;gap:10px}.change-map[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]{grid-template-columns:35px 1fr;gap:0 12px;padding:16px;display:grid}.change-map[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{grid-row:span 2;align-self:center;font-size:1.8rem}.change-map[data-astro-cid-wphdnyj3] h3[data-astro-cid-wphdnyj3]{margin:0 0 6px;font-size:.97rem}.change-map[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{font-size:.8rem}.three-separate[data-astro-cid-wphdnyj3]{grid-template-columns:1fr;gap:11px;padding:20px}.three-separate[data-astro-cid-wphdnyj3] span[data-astro-cid-wphdnyj3]{font-size:.8rem}.three-separate[data-astro-cid-wphdnyj3] b[data-astro-cid-wphdnyj3]{min-width:95px;margin:0;font-size:.62rem;display:inline-block}.three-separate[data-astro-cid-wphdnyj3] i[data-astro-cid-wphdnyj3]{font-size:1.2rem;line-height:1}.activity-options[data-astro-cid-wphdnyj3]{gap:7px}.activity-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]{padding:16px 8px}.activity-options[data-astro-cid-wphdnyj3] strong[data-astro-cid-wphdnyj3]{min-height:32px;font-size:.72rem;line-height:1.4}.activity-options[data-astro-cid-wphdnyj3] .selected-mark[data-astro-cid-wphdnyj3]{width:16px;height:16px;font-size:.62rem;top:10px;right:6px}.activity-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{font-size:1.5rem}.boundary-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]{justify-content:flex-start;padding:10px 7px;font-size:.72rem}.boundary-options[data-astro-cid-wphdnyj3] .selected-mark[data-astro-cid-wphdnyj3]{width:17px;height:17px}.return-label[data-astro-cid-wphdnyj3]{font-size:.81rem}.planner[data-astro-cid-wphdnyj3] input[data-astro-cid-wphdnyj3][type=text]{font-size:.8rem}.plan-note[data-astro-cid-wphdnyj3]{padding:17px}.plan-note[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{font-size:.95rem}.plan-note[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]+p[data-astro-cid-wphdnyj3]{font-size:.78rem}.return-card[data-astro-cid-wphdnyj3]{padding:20px}.return-card[data-astro-cid-wphdnyj3]>div[data-astro-cid-wphdnyj3]{grid-template-columns:1fr;gap:16px}.download-links[data-astro-cid-wphdnyj3]{grid-template-columns:1fr}.downloads[data-astro-cid-wphdnyj3]{padding:21px}.sources[data-astro-cid-wphdnyj3] li[data-astro-cid-wphdnyj3]{font-size:.8rem}}@media (width<=360px){.story[data-astro-cid-wphdnyj3]{padding:0 .8rem}.story-heading[data-astro-cid-wphdnyj3] h1[data-astro-cid-wphdnyj3]{font-size:2.25rem}.hero-heading[data-astro-cid-wphdnyj3] h2[data-astro-cid-wphdnyj3]{font-size:1.85rem}.hero-top[data-astro-cid-wphdnyj3]{gap:8px;font-size:.5rem}.hero-tag[data-astro-cid-wphdnyj3]{font-size:.48rem}.pause-strip[data-astro-cid-wphdnyj3]{gap:8px;margin-left:16px;margin-right:16px}.pause-strip[data-astro-cid-wphdnyj3]>span[data-astro-cid-wphdnyj3]{padding:8px}.pause-strip[data-astro-cid-wphdnyj3] strong[data-astro-cid-wphdnyj3]{padding:8px 11px}.visual[data-astro-cid-wphdnyj3]{padding:1rem .8rem 0}.visual[data-astro-cid-wphdnyj3] figcaption[data-astro-cid-wphdnyj3]{margin-left:-.8rem;margin-right:-.8rem;padding:.85rem .8rem}.forest-chart[data-astro-cid-wphdnyj3]{padding:0 9px}.forest-heading[data-astro-cid-wphdnyj3] h4[data-astro-cid-wphdnyj3]{font-size:.88rem}.forest-heading[data-astro-cid-wphdnyj3] p[data-astro-cid-wphdnyj3]{max-width:145px;font-size:.72rem}.forest-heading[data-astro-cid-wphdnyj3]>strong[data-astro-cid-wphdnyj3]{font-size:1.3rem}.forest-track[data-astro-cid-wphdnyj3]{margin:0 6px}.effect-axis[data-astro-cid-wphdnyj3]{margin:0 15px;font-size:12px}.key-interval[data-astro-cid-wphdnyj3]{width:24px}.boundary-options[data-astro-cid-wphdnyj3]{grid-template-columns:1fr}.activity-options[data-astro-cid-wphdnyj3] strong[data-astro-cid-wphdnyj3]{font-size:.75rem}.activity-options[data-astro-cid-wphdnyj3] button[data-astro-cid-wphdnyj3]{padding:17px 6px 12px}.activity-options[data-astro-cid-wphdnyj3] .selected-mark[data-astro-cid-wphdnyj3]{top:7px;right:5px}.three-separate[data-astro-cid-wphdnyj3] b[data-astro-cid-wphdnyj3]{min-width:88px}}